Behcet's Disease
Overview
Behcet's disease is a rare condition that causes inflammation of blood vessels throughout the body, which can affect the mouth, genitals, skin, eyes, joints, digestive tract and nervous system. It tends to appear in a person's 20s or 30s and is seen more often in people with roots in the Middle East, Turkey, Iran and parts of East Asia such as China and Japan. The exact cause isn't known, but certain genes — including one called HLA-B*51 — appear to play a role, even though testing positive for that gene alone can't confirm the diagnosis.
Questions to Ask Your Doctor
- Based on my mouth sores, genital sores and other symptoms, do I meet the pattern you use to diagnose Behcet's disease?
- Which other organs, like my eyes or digestive tract, need to be checked for involvement?
- Would a topical treatment be enough for my sores, or do you recommend a medication like colchicine or apremilast?
- Under what circumstances would you consider a stronger immune-suppressing medication or a biologic like infliximab?
- What symptoms mean I should be seen urgently rather than waiting for my next scheduled visit?
Getting Care
A rheumatologist typically coordinates care for Behcet's disease, working with other specialists as needed depending on which organs are affected. Seek care promptly for new eye pain, redness or vision changes, since eye involvement is one of the ways this disease can affect the body and is worth assessing quickly.
Keep learning about Behcet's Disease
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